cran-comments.md

In InsightRX/PKPDsim: Tools for Performing Pharmacokinetic-Pharmacodynamic Simulations

Version 1.4.0

This release fixes an issue introduced with an upgrade in Rcpp (1.0.13), as described here: https://github.com/RcppCore/Rcpp/issues/1311.

Minor other fixes include: - Fixed the logic regarding a warning about infusion lengths - Added several example model metadata files, and improve functionality for installing example models - Ensure that paths with spaces are properly parsed - Update debugging informational messages - Make it easier to work with model characteristics - Make sure infusion length can be used with 'sc' or other non-iv administration types - Added feature to allow scaling of the infusion duration - Added feature to calculate AUC pre-ss - Fix interpolation of time-varying covariates in pk blocks. - Fix regimen_to_nm() conversion function - Added requirement that metadata has fixed definition - Minor fixes to warnings and messages

Version 1.3.0

This release addresses the Feb. 16 email from Professor Ripley regarding the use of Boost headers that are not compliant with recent C++ versions.

• Regarding note "Package in Depends/Imports which should probably only be in LinkingTo: ‘BH’":

The BH package provides Boost C++ library headers. The BH library is not used in any of the code in /R or /src, but only in the C++ templates that comes with the package (in /inst/cpp). The C++ templates are used when creating a model using the new_ode_model() function, which is then compiled on-the-fly. If the BH package is removed from the Depends field, it won't be installed and hence models cannot be compiled and run. BH cannot be moved to the LinkingTo field.

InsightRX/PKPDsim documentation built on Aug. 21, 2024, 11:36 p.m.