Description Usage Arguments Details Value
Sliding density scores each segment in signature according to composition of nearby signature.
1 2 | sliding_density(signature, oligos = NULL, window = 100, alpha = c(0.05,
0.025, 0.01))
|
signature |
signature from |
oligos |
either numeric or character vector of oligonucleotides that will be used. If nos specified, whole signature is used. |
window |
size of subset to the left |
alpha |
significance level of scoring intervals. |
Sliding density uses subset of signature centered around single segment and constructs density out of this subset. From this density, credibility intervals are constructed according to significance level alpha and DIAS score is calculated for single segment around which density is centered.
This differs from global density method as DIAS score is calculated only on centered segment, while in global density, DIAS score is calculated for every segment of signature from which density was constructed.
Parameter window
does not specify whole size of subset taken, but only
left and right part. That means that it takes a window left from central
segment and window right. As first segment of signature doesn't have anything
on left and the last segment of signature doesn't have anything on right,
size of actuall subset range from (window+1) to (2*window + 1)
DIAS score for given signature.
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