GetCellResponseData: Get Cell Line Drug Response from FORESEE Object

In JRC-COMBINE/FORESEE: A Tool for the Systematic Comparison of Translational Drug Response Modeling Pipelines

Description

The GetCellResponseData Function extracts the entries of the drug response data that are relevant to predict the drug response with regard to the user's choice of CellResponseType and DrugName. It returns the given input object with a new element "DrugResponse".

Usage

GetCellResponseData(TrainObject, DrugName, CellResponseType)

Arguments

TrainObject	Object that contains all data needed to train a model, including molecular data (such as gene expression, mutation, copy number variation, methylation, cancer type, etc. ) and drug response data
DrugName	Name of the drug whose efficacy is supposed to be predicted with the model
CellResponseType	Format of the drug response data of the TrainObject, such as LN_IC50, AUC, GI50, etc., that is used for prediction

Value

TrainObject

The TrainObject with extracted drug response data.

Examples

GetCellResponseData(GDSC,"Gemcitabine","AUC")

JRC-COMBINE/FORESEE documentation built on Jan. 24, 2020, 1:19 a.m.