NetORA_GS: Network-based enrichment for a list of signatures

Description Usage Arguments Value Author(s) References Examples

Description

This function is wraper of core function NetORA to work on a list of gene sets

Usage

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NetORA_GS(sgList, queryTable, PG, FDR = 0.05)

Arguments

sgList

a vector of gene signature

queryTable

a data frame returned by NetORA_Pre

PG

a vector of background genes

FDR

an FDR cutoff to define gene that are significantly connected a pathway (defaul 0.05)

Value

a list

Author(s)

Jiantao Shi

References

Jiantao Shi: NetORA, a package for network-based pathway over-representation analysis.

Examples

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library("NetORA")
data(text_2006_12_NetGPA)
data(Example_NetGPA)
ExE_Hyper  <- Example_NetGPA$ExE_Hyper
queryTable <- NetORA_Pre(ExE_Hyper, text_2006_12_NetGPA, progressBar = TRUE)
Cancer_GS  <- Example_NetGPA$Cancer_GeneSet
PG <- colnames(text_2006_12_NetGPA)
mergedT <- NetORA_GS(Cancer_GS, queryTable, PG, FDR = 0.05)

JiantaoShi/NetORA documentation built on May 28, 2019, 12:43 p.m.