SeuratLocalMarkers: Find local markers

In KlugerLab/DAseq: Detecting regions of differential abundance between scRNA-seq datasets

Description

Use Seurat FindMarkers() function to identify genes that distinguish a DA region from its local neighborhood

Usage

SeuratLocalMarkers(object, da.slot = "da", da.region.to.run,
  cell.label.slot, cell.label.to.run, ...)

Arguments

object	input Seurat object
da.slot	character, variable name that represents DA regions in Seurat meta.data, default "da"
da.region.to.run	numeric, which (single) DA region to find local markers for
cell.label.slot	character, variable name that represents cell labeling information in Seurat meta.data to combine with DA information
cell.label.to.run	cell label(s) that represent the local neiborhood for the input DA region
...	parameters passed to Seurat FindMarkers() function

Value

a data.frame of markers and statistics

KlugerLab/DAseq documentation built on April 13, 2021, 9:02 p.m.