assignCellClusterNearestNode: Assign cells to a reference cell subtype

In KrishnaswamyLab/phemd: Phenotypic EMD for comparison of single-cell samples

Assign cells to a reference cell subtype

Description

Assigns each cell in cur_cells to a cluster based on nearest cell in Monocle 2 tree

Usage

assignCellClusterNearestNode(
  cur_cells,
  ref_cells,
  ref_cell_labels,
  cell_model = c("monocle2", "seurat", "phate")
)

Arguments

cur_cells	Matrix of cells to be assigned to clusters (Dim: num_cells x num_markers)
ref_cells	Matrix of cells used to build reference Monocle 2 tree (Dim: num_monocle_cells x num_markers)
ref_cell_labels	Vector of length num_monocle_cells containing Monocle 2 cell branch assignments
cell_model	Either "monocle2", "seurat", or "phate" depending on method used to model cell state space

Details

Private method (not exported in namespace). Uses RANN package for fast knn search

Value

Vector of length num_cells representing cluster assignments for each cell in cur_cells

Examples

## Not run: 
cur_cells_cluster_labels <- assignCellClusterNearestNode(cur_cells_expn_data,
clustered_cells_expn_data, clustered_cells_cluster_labels, cell_model='monocle2')

## End(Not run)

KrishnaswamyLab/phemd documentation built on Oct. 2, 2024, 5:10 a.m.