View source: R/preprocessing.R
defineClusters | R Documentation |
Defines polycistronic clusters for a given set of miRNAs based on their chromosomal location. For microRNAs on the human genome (homo sapiens) using mirBAse v22 notation, chromosomal coordinates are provided. These can be used e.g. for data from TCGA. If you use miRNA annotation different from miRBase v22, you must provide your own chromosomal location including chromosome ('chr') and nucleotide position on the chromosome ('pos').
defineClusters(genes, chr, pos, threshold = 10000, ...)
genes |
List of genes for which the miRNA clustering is computed. |
chr |
Optional. Vector that specifies the chromosome for each
miRNA in |
pos |
Optional. Vector of the nucleotice (base-pair) position of
each miRNA in |
threshold |
Maximum distance threshold in base-pairs for the difintion of polycistronic clusters. Default is 10,000, which corresponds to miRBase's cluster definition. |
Vector of clusters. Associates each miRNA in genes
to a
polycistronic cluster.
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