DIGREsyn is developed to predict drug pair synergism/antagonism using Drug Induced Genomic Residual Effect (DIGRE) model. DIGRE utilize drug perturbated cell gene expression profile (GEP), drug dose response curve (DRC) and gene regulatory network (GRN) information (KEGG pathway database or self-provided) to do the prediction, and output the rank of drug pairs from most synergistic to most antagnoistic.
|Author||Jicheng Yang, Sangin Lee, Minzhe Zhang|
|Maintainer||Minzhe Zhang <[email protected]>|
|Package repository||View on GitHub|
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