Minzhe/DIGREsyn: Drug Induced Genomic Residual Effect (DIGRE) model for predicting drug pair synergistic score

DIGREsyn is developed to predict drug pair synergism/antagonism using Drug Induced Genomic Residual Effect (DIGRE) model. DIGRE utilize drug perturbated cell gene expression profile (GEP), drug dose response curve (DRC) and gene regulatory network (GRN) information (KEGG pathway database or self-provided) to do the prediction, and output the rank of drug pairs from most synergistic to most antagnoistic.

Getting started

Package details

AuthorJicheng Yang, Sangin Lee, Minzhe Zhang
MaintainerMinzhe Zhang <[email protected]>
LicenseGPL-3
Version0.2.0
Package repositoryView on GitHub
Installation Install the latest version of this package by entering the following in R:
install.packages("remotes")
remotes::install_github("Minzhe/DIGREsyn")
Minzhe/DIGREsyn documentation built on May 7, 2019, 4:58 p.m.