Minzhe/DIGREsyn: Drug Induced Genomic Residual Effect (DIGRE) model for predicting drug pair synergistic score
DIGREsyn is developed to predict drug pair synergism/antagonism using Drug Induced Genomic Residual Effect (DIGRE) model. DIGRE utilize drug perturbated cell gene expression profile (GEP), drug dose response curve (DRC) and gene regulatory network (GRN) information (KEGG pathway database or self-provided) to do the prediction, and output the rank of drug pairs from most synergistic to most antagnoistic.
Getting started
Browse package contents
Package details |
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| Author | Jicheng Yang, Sangin Lee, Minzhe Zhang |
| Maintainer | Minzhe Zhang <zenroute.mzhang@gmail.com> |
| License | GPL-3 |
| Version | 0.2.0 |
| Package repository | View on GitHub |
| Installation |
Install the latest version of this package by entering the following in R:
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