profileGeneExp: Profiling Drug Treated Gene Expression Data

Description Usage Arguments Details Value Author(s) Examples

Description

This function profile the drug treated gene expression data to prepare the input for DIGREscore function.

Usage

1
profileGeneExp(geneExp)

Arguments

geneExp

a data frame contains the drug treated gene expression data with each column representing one drug, and each row representing one gene. See 'geneExp.demo' for example.

Details

Gene expression is measured after cell is treated by a single compound (or negative control). Raw data (micro array or RNA-Seq) should already be log transformed to have proper scale. This function will average duplicated data with same drug name, and collapse multiple probes to gene level.

Value

a matrix of processed gene expression data.

Author(s)

Jichen Yang, Sangin Lee, Minzhe Zhang(zenroute.mzhang@gmail.com)

Examples

1
geneExpDiff <- profileGeneExp(geneExp = geneExp.demo)

Minzhe/DIGREsyn documentation built on May 7, 2019, 4:58 p.m.