MonashBioinformaticsPlatform/varistran: Variance Stabilizing Transformations appropriate for RNA-Seq expression data

Transform RNA-Seq count data so that variance due to biological noise plus its count-based nature is stable across genes with different average expression levels. This takes the form of a log transformation which is moderated for low counts. Transforming data in this way makes many statistical and machine learning techniques applicable. A Shiny report function showing diagnostic plots based on the transformed data is also provided.

Getting started

Package details

MaintainerPaul Harrison <[email protected]>
LicenseLGPL-2.1 | file LICENSE
Package repositoryView on GitHub
Installation Install the latest version of this package by entering the following in R:
MonashBioinformaticsPlatform/varistran documentation built on Sept. 6, 2018, 1:54 a.m.