Description Usage Arguments Value Author(s) References See Also Examples
given two vectors of diseases and a list of disease-gene associations, this function will calculate disease similarity by method BOG.
1 | BOG(D1, D2, d2g)
|
D1 |
a vector consists disease ids |
D2 |
another vector consists disease ids |
d2g |
a list of disease-gene associations |
a matrix of disease disease simialrity which rownames is D1 and colnames is D2
Peng Ni, Min Li
Mathur S, Dinakarpandian D. Automated ontological gene annotation for computing disease similarity[J]. AMIA Summits on Translational Science Proceedings, 2010, 2010: 12
1 2 3 4 | data(d2g_separation) #get disease-gene associations
ds<-sample(names(d2g_separation),5)
sim<-BOG(ds,ds,d2g_separation)
Normalize(sim) #normalize BOG sim scores
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