NEWS.md

In PerkinElmer/phenoptr: inForm Helper Functions

phenoptr 0.1.1.9007

2018-09-28

• Remove import dependency on tidyverse. Examples and vignettes use dplyr, ggplot2 and magrittr instead. #6

phenoptr 0.1.1.9006

2018-09-28

• New parse_phenotypes function simplifies creation of selectors for select_rows.
• select_rows recognizes the column format of phenotype-per-marker data.
• select_rows treats a NA selector as "select all". This is helpful in lists of selectors.
• read_cell_seg_data attempts to skip microns conversion if it was already done.

phenoptr 0.1.1.9005

2018-07-11

• Fix count_touching_cells to work with two-pixel-wide membrane map. #8

phenoptr 0.1.1.9004

2018-04-24

• Fix count_within_batch to work with cell seg files which don't have Slide ID fields.

phenoptr 0.1.1.9003

• Add density_at_distance and density_bands to estimate cell density at a distance from a boundary.

phenoptr 0.1.1.9002

• Add pixels_per_micron="auto" option to read_cell_seg_data().
• Supports tiled component files using the PerkinElmer fork of the tiff package.

phenoptr 0.1.1.9001

• Faster count_touching_cells when EBImage 4.19.9 is available.

phenoptr 0.1.1.9000

Backwards incompatible changes

• Renamed the package from informr to phenoptr.
• This version changed the order of arguments to subset_distance_matrix in a backwards-incompatible way. This was done to put the csd parameter first, matching other functions with a csd parameter.

New features

• spatial_distribution_report creates an HTML report showing the location and nearest-neighbor relations of cells in a single field.
• count_touching_cells uses morphological analysis of nuclear and membrane segmentation maps to find touching cells of paired phenotypes.
• read_components reads component image files.
• count_within and count_within_batch count the number of from cells having a to cell within a given radius.
• list_cell_seg_files lists all cell seg data files in a folder.
• Added vignettes
  • "Reading and Exploring inForm Tables"
  • "Reading and Displaying inForm Image Files"
  • "Computing Inter-cellular Distances"
  • "Find and count touching cells"
  • "Selecting cells within a cell segmentation table"

Bug fixes

• Better handling of NA values in distance columns of cell seg tables. Previously NA values could cause the column to be read as character data.

Other changes

• read_maps will find the correct path when given a cell seg table path.
• Many documentation improvements.
• Internal cleanup using lintr and goodpractices.
• zlib license

phenoptr 0.1.0.9001

New features

• compute_all_nearest_distance is a convenience function which reads a cell seg table, adds Distance to <phenotype> columns, and writes it out again.

PerkinElmer/phenoptr documentation built on May 30, 2019, 8:01 a.m.