Man pages for Pinlyu3/LRLoop
Two-way communication between cells

apply_hub_corrections_noligandDownweight the hub nodes in the signaling and gene regulatory...
Circos_plotCircos plot
Circos_plot_2Circos plot 2
construct_receptor_target_matrixConstruct a matrix containing receptor-target regulatory...
construct_receptor_tf_matrixConstruct a matrix containing receptor-tf probability scores
construct_tf_target_matrix_noligandConvert gene regulatory network into a matrix.
get_DEGIdentify the differentially expressed genes and the...
get_expr_lrIdentify "expressed" ligand-receptor pairs
get_LRLGet the LRloop L1_R1-L2_R2 pairs
getLRLoopPartnerInfoGet the number and list of LRLoop partners of LRpairs of...
get_LRscoresCalculate the LRscore of each "expressed" ligand-receptor...
getLRscoreupdated_cutoffCalculate an LRscores_LRL-cutoff based on the distribution of...
getnLRloops_randConstruct a specified number of random LRloop networks...
get_pct_exprCalculate the gene detection rate in each condition
L1R1L2R2ScoreCalculate the LRloop score of a L1-R1_L2-R2 pair
L1R1L2R2ScoreHillL1R1L2R2ScoreHill
LRL_info_collectionCollect data on LRloop network relevant ligands and receptors
LRL_statsCalculate some basic statistics on LRloops
LRscoreCalculate the LRscore of an L-R pair
make_discrete_ligand_target_matrix_generalIdentify the targets of each ligand's cognate receptors (1:...
make_LRL_listFind the regulatory relationships of all the (L2-R2)-(L1-R1)...
MostBasicLRinfoPrint: Number of L1-R1 pairs Number of L1 Number of R1 Number...
plotLRLPlot the LRloop network (A_ and B_ in the LR node lables:...
PrepareBasicsGet a list of some basic data info
print_LRL_Score_optionsPrint available options for the function "plotLRL" variable...
take_LR_expr_scoreCreate a dataframe for the expr_scores of L1R1 or L2R2 pairs...
takeNicheNetScoresPut ligand/receptor_activity scores for expressed...
updateLRscoresModify the LRscores of the LRs expressed from ct1 to ct2...
updateLRscores_randGet modified LRscores with random LRloop networks
writeLRLWrite the LRloop_info into .csv files
Pinlyu3/LRLoop documentation built on Jan. 7, 2022, 3:04 p.m.