IncrementsDoseLevels-class: 'IncrementsDoseLevels'

In Roche/crmPack: Object-Oriented Implementation of CRM Designs

IncrementsDoseLevels

Description

IncrementsDoseLevels is the class for increments control based on the number of dose levels.

Usage

IncrementsDoseLevels(levels = 1L, basis_level = "last")

.DefaultIncrementsDoseLevels()

Arguments

levels	(count) see slot definition.
basis_level	(string) see slot definition.

Slots

levels

(count)
maximum number of dose levels to increment for the next dose. It defaults to 1, which means that no dose skipping is allowed, i.e. the next dose can be maximum one level higher than the current base dose. The current base dose level is the dose level used to increment from (see basis_level parameter).

basis_level

(string)
defines the current base dose level. It can take one out of two possible values: last or max. If last is specified (default), the current base dose level is set to the last dose given. If max is specified, then the current base dose level is set to the maximum dose level given.

Note

Typically, end users will not use the .DefaultIncrementsDoseLevels() function.

Examples

# The rule for dose increments which allows for maximum skip one dose level,
# that is 2 dose levels higher than the last dose given.
my_increments <- IncrementsDoseLevels(levels = 2, basis_level = "last")

Roche/crmPack documentation built on April 30, 2024, 3:19 p.m.