IncrementsMaxToxProb-class: 'IncrementsMaxToxProb'

In Roche/crmPack: Object-Oriented Implementation of CRM Designs

IncrementsMaxToxProb

Description

IncrementsMaxToxProb is the class for increments control based on probability of toxicity

Usage

IncrementsMaxToxProb(prob)

.DefaultIncrementsMaxToxProb()

Arguments

prob	(numeric) see slot definition.

Slots

prob

(numeric)
See Usage Notes below.

Usage Notes

For binary models, prob should be a scalar probability.

For ordinal models, prob should be a named vector containing the maximum permissible probability of toxicity by grade. The names should match the names of the yCategories slot of the associated DataOrdinal object.

Note

Typically, end users will not use the .DefaultIncrementsMaxToxProb() function.

Examples

# For use with binary models and data
IncrementsMaxToxProb(prob = 0.35)

# For use with ordinal models and data
IncrementsMaxToxProb(prob = c("DLAE" = 0.2, "DLT" = 0.05))

Roche/crmPack documentation built on Feb. 26, 2025, 1:18 p.m.