LogisticLogNormalSub-class | R Documentation |
LogisticLogNormalSub
LogisticLogNormalSub
is the class for a standard logistic model with
bivariate (log) normal prior with subtractive dose standardization.
LogisticLogNormalSub(mean, cov, ref_dose = 0)
.DefaultLogisticLogNormalSub()
mean |
( |
cov |
( |
ref_dose |
( |
The covariate is the dose x
minus the reference dose x*
,
i.e.:
logit[p(x)] = alpha0 + alpha1 * (x - x*),
where p(x)
is the probability of observing a DLT for a given dose x
.
The prior
(alpha0, log(alpha1)) ~ Normal(mean, cov).
params
(ModelParamsNormal
)
bivariate normal prior parameters.
ref_dose
(number
)
the reference dose x*
.
Typically, end-users will not use the .DefaultLogisticLogNormalSub()
function.
LogisticNormal
, LogisticLogNormal
, ProbitLogNormal
,
ProbitLogNormalRel
.
my_model <- LogisticLogNormalSub(
mean = c(-0.85, 1),
cov = matrix(c(1, -0.5, -0.5, 1), nrow = 2),
ref_dose = 50
)
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