NextBestInfTheory-class: 'NextBestInfTheory'

In Roche/crmPack: Object-Oriented Implementation of CRM Designs

NextBestInfTheory

Description

NextBestInfTheory is the class for next best dose that is based on information theory as proposed in https://doi.org/10.1002/sim.8450.

Usage

NextBestInfTheory(target, asymmetry)

.DefaultNextBestInfTheory()

Arguments

target	(proportion) see slot definition.
asymmetry	(number) see slot definition.

Slots

target

(proportion)
target toxicity probability, except 0 or 1.

asymmetry

(number)
value of the asymmetry exponent in the divergence function that describes the rate of penalization for overly toxic does. It must be a value from (0, 2) interval.

Note

Typically, end users will not use the .DefaultNextBestInfTheory() function.

Roche/crmPack documentation built on April 30, 2024, 3:19 p.m.