Simulations-class: 'Simulations'

In Roche/crmPack: Object-Oriented Implementation of CRM Designs

Simulations

Description

This class captures the trial simulations from model based designs. Additional slots fit, stop_reasons, stop_report,additional_stats compared to the general class GeneralSimulations.

Usage

Simulations(fit, stop_reasons, stop_report, additional_stats, ...)

.DefaultSimulations()

Arguments

fit	(list) see slot definition.
stop_reasons	(list) see slot definition.
stop_report	see Simulations
additional_stats	(list) see slot definition.
...	additional parameters from GeneralSimulations

Slots

fit

(list)
final fits

stop_reasons

(list)
stopping reasons for each simulation run

stop_report

matrix of stopping rule outcomes

additional_stats

list of additional statistical summary

Note

Typically, end users will not use the .DefaultSimulations() function.

Examples

data <- list(
  Data(
    x = 1:2,
    y = 0:1,
    doseGrid = 1:2,
    ID = 1L:2L,
    cohort = 1L:2L
  ),
  Data(
    x = 3:4,
    y = 0:1,
    doseGrid = 3:4,
    ID = 1L:2L,
    cohort = 1L:2L
  )
)

doses <- c(1, 2)

seed <- as.integer(123)

fit <- list(
  c(0.1, 0.2),
  c(0.3, 0.4)
)

stop_report <- matrix(c(TRUE, FALSE), nrow = 2)

stop_reasons <- list("A", "B")

additional_stats <- list(a = 1, b = 1)

simulations <- Simulations(
  fit = fit,
  stop_report = stop_report,
  stop_reasons = stop_reasons,
  additional_stats = additional_stats,
  data,
  doses,
  seed
)

Roche/crmPack documentation built on April 30, 2024, 3:19 p.m.