StoppingCohortsNearDose-class: 'StoppingCohortsNearDose'

In Roche/crmPack: Object-Oriented Implementation of CRM Designs

StoppingCohortsNearDose

Description

StoppingCohortsNearDose is the class for stopping based on number of cohorts near to next best dose.

Usage

StoppingCohortsNearDose(
  nCohorts = 2L,
  percentage = 50,
  report_label = NA_character_
)

.DefaultStoppingCohortsNearDose()

Arguments

nCohorts	(number) see slot definition.
percentage	(number) see slot definition.
report_label	(string or NA) see slot definition.

Slots

nCohorts

(number)
number of required cohorts.

percentage

(number)
percentage (between and including 0 and 100) within the next best dose the cohorts must lie.

Note

Typically, end users will not use the .DefaultStoppingCohortsNearDose() function.

Examples

# Here, is the rule for stopping the study if at least 3 cohorts were dosed
# at a dose within (1 +/- 0.2) of the next best dose.
my_stopping <- StoppingCohortsNearDose(
  nCohorts = 3,
  percentage = 0.2
)

Roche/crmPack documentation built on April 30, 2024, 3:19 p.m.