StoppingPatientsNearDose-class: 'StoppingPatientsNearDose'

In Roche/crmPack: Object-Oriented Implementation of CRM Designs

StoppingPatientsNearDose

Description

StoppingPatientsNearDose is the class for stopping based on number of patients near to next best dose.

Usage

StoppingPatientsNearDose(
  nPatients = 10L,
  percentage = 50,
  report_label = NA_character_
)

.DefaultStoppingPatientsNearDose()

Arguments

nPatients	(number) see slot definition.
percentage	(number) see slot definition.
report_label	(string or NA) see slot definition.

Slots

nPatients

(number)
number of required patients.

percentage

(number)
percentage (between and including 0 and 100) within the next best dose the patients must lie.

Note

Typically, end users will not use the .DefaultStoppingPatientsNearDose() function.

Examples

# As example, here is the rule for stopping the study if at least 9 patients
# were dosed at a dose within (1 +/- 0.2) of the next best dose.

my_stopping <- StoppingPatientsNearDose(
  nPatients = 9,
  percentage = 20
)

Roche/crmPack documentation built on April 30, 2024, 3:19 p.m.