h_model_dual_endpoint_rho: Update 'DualEndpoint' class model components with regard to...

In Roche/crmPack: Object-Oriented Implementation of CRM Designs

Update DualEndpoint class model components with regard to DLT and biomarker correlation.

Description

A simple helper function that takes DualEndpoint model existing components (priormodel, modelspecs, init, sample), and updates them with regard to DLT and biomarker correlation rho.

Usage

h_model_dual_endpoint_rho(use_fixed, rho, comp)

Arguments

use_fixed	(flag) indicates whether a fixed value for DLT and biomarker correlation rho should be used or not. If rho is not supposed to be a fixed value, a prior distribution from the scaled Beta family will be used. See the details below, under rho argument.
rho	(numeric) DLT and biomarker correlation. It must be either a fixed value (between -1 and 1), or a named vector with two elements, named a and b for the Beta prior on the transformation kappa = (rho + 1) / 2, which is in ⁠(0, 1)⁠. For example, ⁠a = 1, b = 1⁠ leads to a uniform prior on rho.
comp	(list) a named list with model components that will be updated. The names should be: priormodel, modelspecs, init, sample. For definitions of the components, see GeneralModel class. The modelspecs and init components on comp list are specified up to the body of corresponding GeneralModel@modelspecs and GeneralModel@init functions. These bodies are simply a lists itself.

Value

A list with updated model components.

Roche/crmPack documentation built on April 30, 2024, 3:19 p.m.