h_next_best_eligible_doses: Get Eligible Doses from the Dose Grid.

In Roche/crmPack: Object-Oriented Implementation of CRM Designs

Get Eligible Doses from the Dose Grid.

Description

Helper function that gets the eligible doses from the dose grid. The eligible doses are the doses which do not exceed a given doselimit. For placebo design, if safety allows (i.e. if there is at least one non-placebo dose which does not exceed the dose limit), the placebo dose it then excluded from the eligible doses.

Usage

h_next_best_eligible_doses(dose_grid, doselimit, placebo, levels = FALSE)

Arguments

dose_grid	(numeric) all possible doses.
doselimit	(number) the maximum allowed next dose.
placebo	(flag) if TRUE the first dose level in the dose_grid is considered as placebo.
levels	(flag) if TRUE the levels of eligible doses are returned, otherwise, the doses (default).

Value

A numeric vector with eligible doses or eligible dose levels if levels flag is TRUE.

Examples

dose_grid <- c(0.001, seq(25, 200, 25))
h_next_best_eligible_doses(dose_grid, 79, TRUE)
h_next_best_eligible_doses(dose_grid, 24, TRUE)

Roche/crmPack documentation built on April 30, 2024, 3:19 p.m.