ct.RRAalphaBatch: Create Batches of Null Permutations for a Crispr Screen

In RussBainer/gCrisprTools: Suite of Functions for Pooled Crispr Screen QC and Analysis

Create Batches of Null Permutations for a Crispr Screen

Description

This is a wrapper function to partition batches of calls to ct.RRAalpha() for multicore processing. It is called internally as a single instance of the beta aggregation step in RRAa. Users should not interact with it directly.

Usage

ct.RRAalphaBatch(
  p,
  g.key,
  result.environment,
  batch.size = 100,
  permutation.seed = NULL
)

Arguments

p	A single column matrix of rank statistics, with row.names indicating the gRNA labels.
g.key	data.frame with guide and gene names
result.environment	The target environment containing the quasi-global variables incremented during the permutations in the child functions.
batch.size	Number of iterations to deploy to each daughter process.
permutation.seed	numeric seed for permutation reproducibility. Default is NULL, in which case no seed is set.

Value

An integer vector indicating the number of iterations in which each gene's score was better than those indicated in result.environment$obs.

Author(s)

Russell Bainer

RussBainer/gCrisprTools documentation built on Nov. 5, 2022, 2:35 p.m.