Description Usage Arguments Details Value Author(s) Examples
For an input character vector of oligonucleotide sequences, this function calculates/predicts a score between 0 and 100. The higher the score, the better the fit to RNase H.
1 | calculate.rnaseh.activity(oligos.lna)
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oligos.lna |
A character vector of oligonucleotide sequences in camel-case (uppercase: LNA, lowercase: DNA) in the 5 to 3 direction. |
The calculation is based on a robust linear model fit to single-point knock-down data against a single target.
Returns a numeric vector of same length as oligos.lna, with each entry between 0 (worst fit) and 100 (best fit).
Peter Hagedorn
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