Description Usage Value Author(s) References See Also Examples
Given an AffyBatch
object fits a robust linear model at probe level and return the residual standard errors and the array effects.
1 | compute.RA(abatch,bg.RA=c("nome","imm","rma"))
|
an object of class RA with a 'data' slot containing a two columns data.frame with IDs as rows and RSE and Array effects as columns.
Stefano Calza <calza@med.unibs.it>, Davide Valentini and Yudi Pawitan.
S. Calza et al. 'Normalization of oligonucleotide arrays based on the least variant set of genes' (2008, BMCBioinformatics).
lvs
, normalize.lvs
, lvs.fit
, normalize.AffyBatch.lvs
fitRA
1 2 3 4 5 6 7 8 | ## Not run:
# Starting from an Affibatch object called aBatch
data.RA <- compute.RA(aBatch)
lvs.id <- lvs.fit(data.RA, proportion=0.6)
lvs.prep <- expresso(aBatch, normalize=FALSE, bgcorrect.method="mas",pmcorrect.method="mas",summary.method="mas")
normalize.AffyBatch.lvs(lvs.prep,lvs.id=lvs.id)
## End(Not run)
|
Add the following code to your website.
For more information on customizing the embed code, read Embedding Snippets.