Description Usage Arguments Value Examples
Filter the depmap annotation file for cell lines of interest.
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 | deepFilter(
DepMap_ID = NA,
stripped_cell_line_name = NA,
CCLE_Name = NA,
alias = NA,
COSMIC_ID = NA,
lineage = NA,
lineage_subtype = NA,
lineage_sub_subtype = NA,
lineage_molecular_subtype = NA,
sex = NA,
source = NA,
Achilles_n_replicates = NA,
max_cell_line_NNMD = NA,
min_cell_line_NNMD = -Inf,
culture_type = NA,
culture_medium = NA,
cas9_activity = NA,
RRID = NA,
sample_collection_site = NA,
primary_or_metastasis = NA,
disease = NA,
disease_subtype = NA,
ageMin = 0,
ageMax = 200,
Sanger_model_ID = NA,
additional_info = NA
)
|
DepMap_ID |
e.g. "ACH-000012" |
CCLE_Name |
e.g. "HCC827_LUNG" |
alias |
alias |
COSMIC_ID |
e.g. "1240146" |
lineage |
lineage, e.g. "leukemia" or "lung" |
lineage_subtype |
sublineage, e.g. "AML", "ALL", etc. |
lineage_sub_subtype |
Subsublineage |
lineage_molecular_subtype |
lineage molecular subtype |
sex |
either "Male" or "Female" |
source |
e.g. "Sanger", "DSMZ" |
Achilles_n_replicates |
minimum number of replicates |
culture_type |
mostly "Adherent" or "Suspension" |
culture_medium |
culture medium |
RRID |
e.g. "CVCL_0001" |
sample_collection_site |
e.g. "lung" |
primary_or_metastasis |
either "Primary" or "Metastasis" |
disease |
disease of the patient, e.g. "Lung Cancer" |
disease_subtype |
subdisease of the patient |
ageMin |
integer, minimum patient age |
ageMax |
integer, maximum patient age |
Sanger_model_ID |
e.g. "SIDM01067" |
additional_info |
additional information |
cell_line_name |
e.g. "HCC827" |
max_cell_line_NMMD |
negative number, NMD = nonsense-medieated mRNA decay |
min_cell_line_NMMD |
negative number, NMD = nonsense-medieated mRNA decay |
Cas9_activity |
minimum Cas9 activity, positive number |
A data.frame where each row is a human cell line, and each column is a parameter of information about the cell line (e.g. ID, tissue, etc.). Note that terms are searched for with grepl, so use ^ and $ to determine ending and start if need be.
1 2 | head(deepFilter())
a <- seepFilter(lineage_subtype="^AML$", ageMin=60)
|
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