dmelER contains allele count data of an evolve and resequence (E&R) study conducted with Drosophila melanogaster.
dmelER is a
Three replicated founder populations were set up based on 113 isofemale lines established from a natural Northern Portuguese population of D. melanogaster. The three populations were propagated as independent replicates in a hot fluctuating laboratory environment, with 28°C and 18°C during light and dark periods, respectively. At multiple time points (F0, F15, F37 and F59) Pool-seq was applied to obtain genome-wide allele frequency estimates for each of the three replicates. Temporal allele frequencies are available for a subset of about 15,000 genomic loci.
Orozco-terWengel P., Kapun M., Nolte V., Kofler R., Flatt T., & Schlötterer C.: Adaptation of Drosophila to a novel laboratory environment reveals temporally heterogeneous trajectories of selected alleles, Molecular Ecology 2012, 21, 4931–41.
Franssen S. U., Nolte V., Tobler R., & Schlötterer C.: Patterns of linkage disequilibrium and long range hitchhiking in evolving experimental Drosophila melanogaster populations, Molecular Biology and Evolution 2015, 32, 495–509.
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