densBiref: Estimate Birefringence of Bone Tissue From Mineral Density

In TobinH/microTransit: Quantitative Polarized Light Imaging and Analysis Tools

Estimate Birefringence of Bone Tissue From Mineral Density

Description

densBiref uses a simple analytical approach to estimating birefringence from bone mineral density, as expressed in "milligrams of hydroxyapatite per cubic centimeter" (mgHA/ccm).

Usage

densBiref(density, dHA = 3.16, birefHA = -0.004, birefC = 0.008933)

Arguments

density	estimate of mineral density in the sample, in units of mgHA/ccm.
dHA	density of hydroxyapatite in SI units. Default is 3.16.
birefHA	birefringence of hydroxyapatite. Default is -4e-3.
birefC	birefringence of collagen. Default is 8.933e-3.

Details

The actual relationship between bone mineral density and birefringence is complicated, because much of the birefringence of collagen is form birefringence (Dallemagne and Mélon 1946; Ascenzi and Bonucci 1961), but this approach provides a useful heuristic.

Value

Numeric value giving the estimated birefringence.

References

Ascenzi, A., & Bonucci, E. (1961). A quantitative investigation of the birefringence of the osteon. Acta Anatomica, 44(3), 236-262.

Dallemagne, M. J., & Melon, J. (1946). Nouvelles recherches relatives aux propriétés optiques de l'os: La biréfringence de l'os minéralisé; Relations entre les fractions organiques et inorganiques de l'os. Journal of the Washington Academy of Sciences, 36(6), 181-195.

See Also

Other qPLM Input Functions: buildqPLM()

TobinH/microTransit documentation built on Jan. 19, 2024, 5:21 a.m.