updateMstepFQC: Update the parameter F and Q (M-step in the EM-algorithm)

In USCbiostats/HiLDA: Conducting statistical inference on comparing the mutational exposures of mutational signatures by using hierarchical latent Dirichlet allocation

Description

Update the parameter F and Q (M-step in the EM-algorithm)

Usage

updateMstepFQC(
  vPatternList,
  vSparseCount,
  nTheta,
  fdim,
  signatureNum,
  sampleNum,
  patternNum,
  samplePatternNum,
  isBackground
)

Arguments

vPatternList	The list of possible mutation features (converted to a vector)
vSparseCount	The table showing (mutation feature, sample, the number of mutation) (converted to a vector)
nTheta	The parameters in the distribution
fdim	a vector specifying the number of possible values for each mutation signature
signatureNum	the number of mutation signatures
sampleNum	the number of cancer genomes
patternNum	the number of possible combinations of all the mutation features
samplePatternNum	the number of possible combination of samples and mutation patternns
isBackground	the logical value showing whether a background mutaiton features is included or not

Value

a vector

USCbiostats/HiLDA documentation built on Oct. 15, 2021, 10:22 a.m.