mgoSim | R Documentation |
Given two GO term sets, this function will calculate the semantic similarity between them, and return their semantic similarity
mgoSim(GO1, GO2, semData, measure = "Wang", combine = "BMA")
GO1 |
A set of go terms. |
GO2 |
Another set of go terms. |
semData |
GOSemSimDATA object |
measure |
One of "Resnik", "Lin", "Rel", "Jiang", "TCSS" and "Wang" methods. |
combine |
One of "max", "avg", "rcmax", "BMA" methods, for combining semantic similarity scores of multiple GO terms associated with protein or multiple proteins assiciated with protein cluster. |
similarity
Yu et al. (2010) GOSemSim: an R package for measuring semantic similarity among GO terms and gene products Bioinformatics (Oxford, England), 26:7 976–978, April 2010. ISSN 1367-4803 http://bioinformatics.oxfordjournals.org/cgi/content/abstract/26/7/976 PMID: 20179076
goSim
geneSim
mgeneSim
clusterSim
mclusterSim
d <- godata('org.Hs.eg.db', ont="MF", computeIC=FALSE)
go1 <- c("GO:0004022", "GO:0004024", "GO:0004023")
go2 <- c("GO:0009055", "GO:0020037")
mgoSim("GO:0003824", go2, semData=d, measure="Wang")
mgoSim(go1, go2, semData=d, measure="Wang")
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