beta.data: Beta Data Of SNP Regressed on Causal Variables and Disease
In Yuande/GMRP: GWAS-based Mendelian Randomization and Path Analyses
Description
Usage
Format
Details
Value
Source
References
Examples
Description
Beta data are a matrix dataset consisting of 5 columns: cad, ldl, hdl, tg, and tc with 368 rows.
Usage
1
data("beta.data")
Format
A data frame with 368 observations on the following 5 variables.
cada numeric vector
ldla numeric vector
hdla numeric vector
tga numeric vector
tca numeric vector
Details
Beta data are a matrix consisting of regression coefficients of 368 SNPs on cad, ldl, hdl, tg, tc where cad is coronary artery disease, ldl is low-density lipoprotein cholesterol, hdl, high-density lipoprotein cholesterol, tg,triglycerides and tc, total cholesterol in plasma. These 368 SNPs were obtained by using mktable from GWAS meta-analyzed data.
Value
A set of real regression coefficients of 368 SNPs on disease and causal variables.
Source
http://csg.sph.umich.edu//abecasis/public/lipids2013/
\http://www.cardiogramplusc4d.org/downloads/
References
Willer CJ et al. Discovery and refinement of loci associated with lipid levels. Nat. Genet. 2013. doi:10.1038/ng.2797.
\Schunkert, H. et al. 2011. Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. Nat Genet 43: 333-338.[online]
\Schunkert H, Konig IR, Kathiresan S, Reilly MP, Assimes TL, Holm H et al. Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. Nat Genet. 2011 43: 333-338.
Examples
1
2
Yuande/GMRP documentation built on May 29, 2019, 11:04 p.m.
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Description Usage Format Details Value Source References Examples
Description
Beta data are a matrix dataset consisting of 5 columns: cad, ldl, hdl, tg, and tc with 368 rows.
Usage
1 | data("beta.data")
|
Format
A data frame with 368 observations on the following 5 variables.
cada numeric vector
ldla numeric vector
hdla numeric vector
tga numeric vector
tca numeric vector
Details
Beta data are a matrix consisting of regression coefficients of 368 SNPs on cad, ldl, hdl, tg, tc where cad is coronary artery disease, ldl is low-density lipoprotein cholesterol, hdl, high-density lipoprotein cholesterol, tg,triglycerides and tc, total cholesterol in plasma. These 368 SNPs were obtained by using mktable from GWAS meta-analyzed data.
Value
A set of real regression coefficients of 368 SNPs on disease and causal variables.
Source
http://csg.sph.umich.edu//abecasis/public/lipids2013/
\http://www.cardiogramplusc4d.org/downloads/
References
Willer CJ et al. Discovery and refinement of loci associated with lipid levels. Nat. Genet. 2013. doi:10.1038/ng.2797.
\Schunkert, H. et al. 2011. Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. Nat Genet 43: 333-338.[online]
\Schunkert H, Konig IR, Kathiresan S, Reilly MP, Assimes TL, Holm H et al. Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. Nat Genet. 2011 43: 333-338.
Examples
1 2 |
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