cad.data: boldGWAS Meta-analyzed Data of Coronary Artery Disease
In Yuande/GMRP: GWAS-based Mendelian Randomization and Path Analyses

Description Usage Format Details Value Source References Examples

cad.data are a matrix dataset consisting of 12 variables such as SNPID, SNP position on chromosomes, allele and alternative allele, allelic frequencies and 1069 SNPs.

1	data("cad.data")

A data frame with 1609 observations on the following 12 variables.

SNP: a character vector
chr_pos_b36: a character vector
reference_allele: a character vector
other_allele: a character vector
ref_allele_frequency: a numeric vector
pvalue: a numeric vector
het_pvalue: a numeric vector
log_odds: a numeric vector
log_odds_se: a numeric vector
N_case: a numeric vector
N_control: a numeric vector
model: a character vector

cad.data, also called CARDIoGRAM GWAS, are a meta-analyzed GWAS data from GWAS studies of European descent imputed to HapMap2 involving 22,233 cases and 64,762 controls. The data were downloaded from the following website.

A data sheet consisting of 1609 rows(SNPs) and 12 columns(character vectors such as SNPID and allele, numeric vector such as allele frequency and beta coefficient. See data format above).

http://www.cardiogramplusc4d.org/downloads/

Schunkert H, Konig IR, Kathiresan S, Reilly MP, Assimes TL, Holm H et al. Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. Nat Genet. 2011 43: 333-338.