View source: R/go_multinomial.R
go_multinomial
is a function used to run GO analysis on multi-class labeled ranged data. The back ground used is the shared genes in all of the ranges.
1 2 3 4 5 | go_multinomial(Y, row_ranges, txdb, orgDb, HDER = "GO_multinomial",
category = "BP", gene_key = "ENTREZID", min_bg_count = 10,
min_gs_count = 10, max_bg_count = 500, max_gs_count = 500,
pvalue_correction = "BH", GO_Slim = FALSE, EASE_Score = TRUE,
top_terms = 10, save_chart = FALSE, background_ranges = NULL)
|
Y |
A |
row_ranges |
A |
txdb |
A |
orgDb |
An |
HDER |
A |
category |
A character specifying the gene ontology category, can be one of "BP", "CC", and "MF", default "BP". |
gene_key |
A character specifying the type of the gene ID, the available types of the keys can be find using |
min_bg_count |
Term minimum number of occurence in background genes; default 10. |
min_gs_count |
Term minimum number of occurence in gene set genes; default 10. |
max_bg_count |
Term maximum number of occurence in background genes; default 500. |
max_gs_count |
Term maximum number of occurence in gene set genes; default 500. |
pvalue_correction |
Method used for multiple hypothesis adjustment, can be one in "holm", "hochberg", "hommel", "bonferroni", "BH", "BY","fdr", and "none". |
GO_Slim |
Whether to conduct enrichment analysis only on GO slim terms (a certain subset to GO terms), default FALSE. |
EASE_Score |
Whether or not use EASE score method. (a more conservative hypergeomatric test calculation used in DAVID) for more details please refer to here, default TRUE. |
top_terms |
Top number of terms (sorted by p values) for each multinomial class returned in the analysis, default is 10. |
save_chart |
Whether to save the chart of GO enrichment for each calss, default FALSE. |
background_ranges |
A |
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