Description Usage Arguments Value
Calculate prior probability of being a risk SNP
1 2 3 4 5 6 | calc.priors(object, effect = 2, adjust = NULL, verbose = FALSE,
trace = 0)
## S4 method for signature 'GWAS'
calc.priors(object, effect = 2, adjust = NULL,
verbose = FALSE, trace = 0)
|
object |
|
effect |
assumed effect size, used to shift the ideal z-score distribution |
adjust |
optional parameter to adjust P(R) for linkage disequilibrium |
verbose |
print out intermediate statistics calculated during the analysis |
trace |
Non-negative integer. If positive, tracing information on the
progress of the optimization is produced. See |
A list with components:
p.r
P(R): prior probability of being a risk SNP
p.n
P(N): prior probability of a SNP having no effect
lambda
GWAS inflation factor (λ)
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