sim.QTL.data.LD: Simulates subjects for continuous outcome

In agaye/ESPRESSO.LD: Power Analysis and Sample Size Calculation for two SNPs in Linkage Disequilibrium

Description

Generates the specified number of subjects

Usage

sim.QTL.data.LD(n = NULL, ph.mean = NULL, ph.sd = NULL, freq1 = NULL,
  freq2 = NULL, g1.model = NULL, g1.efkt = NULL, g2.model = NULL,
  g2.efkt = NULL, ld = NULL, r = NULL, pheno.rel = NULL)

Arguments

n	Number of subjects to simulate
ph.mean	statistical mean
ph.sd	standard deviation
freq1	Minor allele frequency if the 1st of the two genetic variant
freq2	Minor allele frequency if the 2nd of the two genetic variant
g1.model	Genetic model; 0 for binary and 1 for additive
g1.efkt	Effects of the 1st genetic variant
g2.model	Genetic model; 0 for binary and 1 for additive
g2.efkt	Effects of the 2nd genetic variant
r	desired level of correlation if the two SNPs are modelled as being in LD.
pheno.rel	reliability of the assessment for a quantitative outcome.

Value

A matrix

Author(s)

Gaye A.

agaye/ESPRESSO.LD documentation built on May 10, 2019, 7:31 a.m.