Description Usage Arguments Details Value Author(s) See Also Examples
These functions provide a simple way to run all steps of RaMWAS pipeline.
1 2 3 4 5 6 7 8 9 10 11 12 | ramwas1scanBams(param)
pipelineProcessBam(bamname, param)
ramwas2collectqc(param)
ramwas3normalizedCoverage(param)
ramwas4PCA(param)
ramwas5MWAS(param)
ramwas6annotateTopFindings(param)
ramwas7ArunMWASes(param)
ramwas7BrunElasticNet(param)
ramwas7CplotByNCpGs(param)
ramwas7riskScoreCV(param)
ramwasSNPs(param)
|
param |
List with RaMWAS parameters. |
bamname |
Name of the BAM file to process.
Can be absolute or relative to |
See vignettes for details: browseVignettes("ramwas")
.
Function pipelineProcessBam
returns "OK. <bamname>"
if no error occurred. Otherwise, returns text with error.
Other functions return nothing.
Andrey A Shabalin andrey.shabalin@gmail.com
See vignettes: browseVignettes("ramwas")
.
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 | param = ramwasParameters(
dirbam = "/project/bams",
dirproject = "/project",
filebamlist = "000_list_of_files.txt",
scoretag = "AS",
minscore = 100,
cputhreads = 4,
filecpgset = "/RaMWAS/hg19_1kG_MAF_0.01_chr1-22_bowtie2_75bp.rds",
filenoncpgset = "/RaMWAS/hg19_1kG_MAF_0.01_chr1-22_bowtie2_75bp_nonCpG.rds",
maxrepeats = 3,
maxfragmentsize = 250,
minfragmentsize = 75,
filebam2sample = "000_list_of_files.txt",
filecovariates = "Covariates.txt",
modelcovariates = c("Age","Sex"),
modeloutcome = "CellType",
modelPCs = 1,
cvnfolds = 10,
mmncpgs = 1000,
mmalpha = 0
)
## Not run:
ramwas1scanBams(param)
ramwas2collectqc(param)
ramwas3normalizedCoverage(param)
ramwas4PCA(param)
ramwas5MWAS(param)
ramwas6annotateTopFindings(param)
ramwas7riskScoreCV(param)
## End(Not run)
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