Man pages for bhattacharya-a-bt/isoTWAS
Isoform-level transcriptome-wide association studies
| bayes_factor | Compute Bayes factors for TWAS Z-scores |
| burdenTest | Compute weighted burden test |
| compute_blup | Univariate BLUP on all columns |
| compute_curds_whey | Breiman and Friedman's curds and whey multivariate regression... |
| compute_finemap_regress | Fine-mapping and clustering SEs with SUR |
| compute_fixed | Multivariate regression with covariance estimate |
| compute_isotwas | Compute isoTWAS model for a set of isoforms/transcripts |
| compute_mrce | Multivariate regression with covariance estimate |
| compute_omega | Compute precision matrix between isoforms |
| conditional_test | Conditional gene-level test |
| conditional_test_focus | Conditional gene-level test |
| convert_model | Convert isotwas model list to tibble |
| curds_whey | Breiman and Friedman's curds and whey multivariate regression |
| estimate_cor | Compute correlation for fine-mapping |
| finemap_regress | Fine-mapping and clustering SEs with SUR |
| get_resid | Compute residuals for Z-scores |
| multivariate_elasticnet | Multivariate elastic net on all columns with row-wise penalty |
| multivariate_joinet | Multivariate stacked elastic net on all columns using joinet |
| multivariate_spls | Multivariate sparse partial least squares |
| p_confirm | Compute confirmation P-value for one gene |
| p_screen | Compute screening P-value for one gene |
| twas_finemap | FOCUS-like gene-level finemapping |
| univariate_blup | Univariate BLUP on all columns |
| univariate_elasticnet | Univariate elastic net on all columns |
| univariate_susie | Univariate SuSiE on all columns |
