bayes_factor: Compute Bayes factors for TWAS Z-scores

In bhattacharya-a-bt/isoTWAS: Isoform-level transcriptome-wide association studies

Compute Bayes factors for TWAS Z-scores

Description

The function runs a modified version of FOCUS's Bayes factor calculation

Usage

bayes_factor(
  zscores,
  idx_set,
  wcor,
  prior_chisq = 40,
  prb = 0.001,
  use_log = T
)

Arguments

zscores	numeric, vector of Z-scores
idx_set	character, ids of transcripts
wcor	numeric, correlation matrix from estimate_cor
prior_chisq	numeric, prior for chi-square mean
prb	numeric, prior for causal configuration
use_log	logical, use log of bayes factors

Value

bayes factor vector

bhattacharya-a-bt/isoTWAS documentation built on Jan. 9, 2025, 10:25 p.m.