compute_omega: Compute precision matrix between isoforms

In bhattacharya-a-bt/isoTWAS: Isoform-level transcriptome-wide association studies

Compute precision matrix between isoforms

Description

The function computes the covariance and precision matrix between columns of the isoform matrix

Usage

compute_omega(
  Y,
  Y.rep,
  R,
  id,
  method = c("replicates", "mean"),
  nlambda = 15,
  verbose = F
)

Arguments

Y	matrix, matrix of G mean isoform expression across columns
Y.rep	matrix, matrix of G isoform expression with replicates
R	int, number of replicates
id	vector, vector of sample ids showing rep to id
method	character, use Y.rep or Y
nlambda	int, number of matrices to produce in terms of sparsity
verbose	logical

Value

covariance and/or precision matrix list in huge form

bhattacharya-a-bt/isoTWAS documentation built on Jan. 9, 2025, 10:25 p.m.