combiner.missing: Run lm on each column in a cluster and combine p-values with...

In brentp/clustermodelr: Models on clusters of correlated data

Description

Run lm on each column in a cluster and combine p-values with the Stouffer-Liptak method or the z-score method. Missing data OK.

Usage

combiner.missing(formula, covs, meth, weights = NULL,
  cor.method = "spearman", combine.fn = stouffer_liptak.combine)

Arguments

formula	an R formula containing "methylation"
covs	covariate data.frame containing the terms in formula except "methylation" which is added automatically
meth	a matrix of correlated data.
weights	optional weights matrix of same shape as meth
cor.method	either "spearman" or "pearson"
combine.fn	a function that takes a list of p-values and a correlation matrix and returns a combined p-value stouffer_liptak.combine or zscore.combine

Value

list(covariate, p, coef) where p and coef are for the coefficient of the first term on the RHS of the model.

brentp/clustermodelr documentation built on May 13, 2019, 5:11 a.m.