For every method except mixed_model, one or more of the arguments must be specified. To run a linear model, simply send the formula in lme4 syntax
1 2 3 |
formula |
an R formula containing "methylation" |
covs |
covariate data.frame containing the terms in formula except "methylation" which is added automatically |
meth |
a matrix of correlated data. |
weights |
matrix of weights with same dim as of rows
as |
gee.corstr |
if specified, the the corstr arg to geeglm. gee.idvar must also be specified. |
gee.idvar |
if specified, the cluster variable to geeglm |
counts |
if specified, then use poisson or NB where available |
bumping |
if true then the bumping algorithm is used. |
combine |
either "liptak" or "z-score" used to get a single p-value after running a test on each probe. |
skat |
use the SKAT method to test associated. In
this case, the model will look like: |
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