drugDB: CellMiner Drug Response Values

In cannin/rcellminer: rcellminer: Molecular Profiles, Drug Response, and Chemical Structures for the NCI-60 Cell Lines

CellMiner Drug Response Values

Description

CellMiner Drug Response Values

Details

A list containing response values and annotations:

• act Z-scores of the averaged negative log GI (growth inhibition) 50 values across repeats for the NCI-60; assay described here: http://dtp.nci.nih.gov/branches/btb/ivclsp.html

• annot

  • id Dataset identifier; NOTE: DO NOT use this column; the NSC is the primary drug identifier

  • nsc National Service Center identifier; the primary drug identifier

  • name Compound name

  • brand_name Brand name for the compound, if sold commericially

  • formula Compound chemical formula

  • testing_status Information on whether it is known if the compound is FDA approved or undergoing testing in clinical trials

  • source TODO

  • smiles Compound chemical structure as a SMILES string

  • weight Compound chemical weight in g/mol

  • mechanism Pharmacological mechanism of action

  • confidential_flag A flag to indicate if compound information is public

  • total_probes TODO

  • total_good_probes TODO

  • low_correlations TODO

  • failure_reason TODO

  • cas CAS Registry Number; NOTE: Due to data restrictions PubChem IDs are the preferred mapping ID to other datasets

  • pubchem_id PubChem ID

Author(s)

Vinodh Rajapakse vinodh.rajapakse AT nih.gov

References

http://discover.nci.nih.gov/cellminer/loadDownload.do

cannin/rcellminer documentation built on Aug. 11, 2024, 8:45 a.m.