R/data_YATES_BREAST_NATMED_2015.R

In caravagn/evoverse.datasets: Data released in the evoverse

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# Yates breat cancer
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#' Mutations and copy number from breast cancer patients (PMID: 26099045).
#' n = 50 patients, multi-region whole-exome sequencing. Calls generated from
#' Yates et al. (PMID: 26099045).
#'
#' @docType data
#'
#' @usage data(YATES_BREAST_NATMED_2015)
#'
#' @format Data for the breast cancer cohort by Yates et al. The data has been extracted
#' from the Supplementary tables released in the original Nature Medicine paper (PMID: 26099045).
#' Mutations and copy number are reported as present or absent in each one of the sequenced
#' biopsies. All the data (calls, definition of driver events, etc.) is as released in the
#' original paper. The data is as used in the paper Caravagna et al (PMID: 30171232) to show
#' repeated evolution in breast cancers with REVOLVER.
#'
#' @keywords datasets
#'
#' @references Yates, L.R., Gerstung, M., Knappskog, S., Desmedt, C., Gundem, G., Van Loo, P.,
#' Aas, T., Alexandrov, L.B., Larsimont, D., Davies, H. et al., 2015. Subclonal
#' diversification of primary breast cancer revealed by multiregion sequencing.
#' Nature Medicine, 21(7), p.751. PMID: 26099045
#'
#' @examples
#' data(YATES_BREAST_NATMED_2015)
#' YATES_BREAST_NATMED_2015
"YATES_BREAST_NATMED_2015"