refine_denovo_signatures | R Documentation |
Function to refine the inferred de novo signatures. The function performs a linear combination between de novo and reference signatures. If a de novo signature can be explained as a linear combination of one or more reference signatures, it will be removed and its exposures will be distributed among the similar signatures.
refine_denovo_signatures(x, types = get_types(x))
x |
bascule object. |
types |
List of variant types to perform de novo refinement on. |
bascule object.
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