chariff/Cytometree: Automated Cytometry Gating and Annotation

Given the hypothesis of a bi-modal distribution of cells for each marker, the algorithm constructs a binary tree, the nodes of which are subpopulations of cells. At each node, observed cells and markers are modeled by both a family of normal distributions and a family of bi-modal normal mixture distributions. Splitting is done according to a normalized difference of AIC between the two families.

Getting started

Package details

AuthorChariff Alkhassim, Boris Hejblum, Anthony Devaux, Van Hung Huynh Tran
MaintainerBoris Hejblum <[email protected]>
LicenseLGPL-3 | file LICENSE
Package repositoryView on GitHub
Installation Install the latest version of this package by entering the following in R:
chariff/Cytometree documentation built on Dec. 12, 2018, 8:40 p.m.