parametric_simulations: Replicate parametric simulations for power analyses

In cozygene/CellTypeSpecificMethylationAnalysis: Evaluation of Cell Type Specific Methylation Analysis

Description

Replicate parametric simulations for power analyses

Usage

parametric_simulations(
  data_dir,
  results_dir,
  plot_dir,
  plot_type = "tiff",
  experiment_index = c(1, 2, 3, 4),
  num_cores = 1,
  m = 1000,
  m.true = 100,
  effect_sizes = 1:8,
  n = 500,
  num_sims = 50
)

Arguments

data_dir	Path to directory to store data
results_dir	Path to directory to store results
plot_dir	Path to directory to store plots
plot_type	Type of image to save plot
experiment_index	An integer in 1, 2, 3, or 4. 1 specifies phenotype affecting cell-type-specific methylation levels. 2 specifies the same as one but true positives also consider predicted direction. 3 specifies the phenotype being affected by cell-type-specific methylation levels. 4 is the same as 1 with smaller sample size
num_cores	Number of cores to use for analysis
m	Number CpGs to simulate
m.true	Number of true associations
effect_sizes	Vector of effect sizes to simulate
n	Sample size
num_sims	Number of simulations to run

Value

None (TODO: Return a list of results)

cozygene/CellTypeSpecificMethylationAnalysis documentation built on Jan. 28, 2022, 11:20 a.m.