Description Usage Format References
Simulated data set to represent the genetics of the Ari people, as reported in van Dorp et al PLoS Genetics 2015 11(8): e1005397, and followed up in Falush, van Dorp & Lawson http://biorxiv.org/content/early/2016/07/28/066431.
This dataset was simulated to understand the Ari people, who are culturally split into "Blacksmiths" and "Cultivators". There was much discussion whether the Blacksmiths were a better representative of an ancient African population, or whether they were simply marginalised and hence had experienced genetic drift that made them look different to other populations. Package badMIXTURE
allows you to test exactly this.
This simulation follows the so-called "Remnants" scenario, in which the truth is that the "Ari Blacksmiths" (Population 13) are the last remnants of an ancient population mixed with a recent one, whilst the "Ari Cultivators" (population 5) are admixed between these and other modern populations. The mixture solution (arisim_remnants$mix
produced with ADMIXTURE, Alexander, Novembre & Lange 2009, Genome Research 19:1655-1664) gets this wrong but the residual plots (arisim_remnants$data
produced with ChromoPainter, Lawson, Hellenthal, Myers & Falush 2012, PLoS Genetics, e1002453) highlight this.
See compareMixtureToData
) and the examples within for how to understand this data.
1 |
arisim_remnants contains the following items:
mixture : the ADMIXTURE (mixture) estimate for these data
data : The ChromoPainter results for these data
ids : The mapping of individuals into groups
#' @source http://biorxiv.org/content/early/2016/07/28/066431
http://biorxiv.org/content/early/2016/07/28/066431
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