#'
#' @title Fit a natural effect model
#' @description This function is similar to R function \code{neModel} from the
#' \code{medflex} package.
#' @details The function \code{ds.neModel} is used to fit a natural effect model on the
#' expanded dataset. For more details see the help file of the \code{neModel} function
#' in the \code{medflex} package.
#' @param formula a formula object providing a symbolic description of the
#' natural effect model.
#' @param family a description of the error distribution and link function to be
#' used in the model. For glm this can be a character string naming a family
#' function, a family function or the result of a call to a family function.
#' For glm.fit only the third option is supported.
#' @param expData the expanded dataset (of class "expData").
#' @param se character string indicating the type of standard errors to be calculated.
#' By default robust se are calculated. NOTE: In version 1.0.0 the "bootstrap" method
#' does not work properly
#' @param nBoot number of bootstrap replicates.
#' @param newobj a character string that provides the name for the output object
#' that is stored on the data servers. Default \code{neModel.out}.
#' @param datasources a list of \code{\link{DSConnection-class}}
#' objects obtained after login. If the \code{datasources} argument is not specified
#' the default set of connections will be used: see \code{\link{datashield.connections_default}}.
#' @return a summary table of the object of class 'neModel'.
#' @author Demetris Avraam, for DataSHIELD Development Team
#' @export
#'
ds.neModel <- function(formula = NULL, family = NULL, expData = NULL, se = "robust",
nBoot = 1000, newobj = NULL, datasources = NULL){
# look for DS connections
if(is.null(datasources)){
datasources <- DSI::datashield.connections_find()
}
# ensure datasources is a list of DSConnection-class
if(!(is.list(datasources) && all(unlist(lapply(datasources, function(d) {methods::is(d,"DSConnection")}))))){
stop("The 'datasources' were expected to be a list of DSConnection-class objects", call.=FALSE)
}
# verify that 'formula' was set
if(is.null(formula)){
stop(" Please provide a valid regression formula!", call.=FALSE)
}
# if the argument 'expData' is set, check that the data frame is defined (i.e. exists) on the server side
if(!(is.null(expData))){
defined <- dsBaseClient:::isDefined(datasources, expData)
}
# check if the all the variables in the model are defined in all studies
formula <- stats::as.formula(formula)
model_vars <- all.vars(formula)
lapply(model_vars, function(x){dsBaseClient:::isDefined(datasources, paste0(expData, "$", x))})
# check that 'family' was set
if(is.null(family)){
stop(" Please provide a valid 'family' argument!", call.=FALSE)
}
# check if 'se' is either 'bootstrap' or 'robust'
if(!(se %in% c("bootstrap", "robust"))){
stop(" Argument 'se' must be either 'bootstrap' or 'robust'!", call.=FALSE)
}
if(is.null(newobj)){
newobj <- 'neModel.out'
}
calltext <- call('neModelDS', formula, family, expData, se, nBoot, newobj)
out <- DSI::datashield.aggregate(datasources, calltext)
return(out)
}
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