MultiSKAT.Kinship.example.data: Example data for MultiSKAT with related samples

In diptavo/MultiSKAT: Sequence Kernel Association Tests with Multiple phenotypes

Description

This is a dataset of 5 phenotypes for 500 individuals genotyped across 20 variants. For this dataset, variants at 2, 5, 11 and 20 are set to be causal. Phenotypes 1, 2 and 3 are associated with the causal SNPs. The effect sizes of individual SNPs are proportional to logarithm of their minor allele frequencies.

Usage

data("MultiSKAT.Kinship.example.data")

Format

MultiSKAT.example.data contains the following objects:

• Phenotypes : A matrix of 5 phenotypes for 500 individuals with individuals as rows and phenotypes as columns.

• Genotypes : A matrix of Genotype values for 500 individuals across 20 variants with individuals as rows and variants as columns

• Cov : A vector of intercept covariates for 500 individuals.

• Kinship: A Kinship matrix for the 500 individuals

• V_g: A co-heritability matrix for 5 phenotypes

• V_e: A residual variance matrix for the 5 phenotypes

• U: Spectral vector matrix of the Kinship matrix

• D: Spectral values matrix of the Kinship matrix

Examples

data(MultiSKAT.Kinship.example.data)
attach(MultiSKAT.Kinship.example.data)
Phenotypes[1:4,1:5]

diptavo/MultiSKAT documentation built on May 22, 2019, 1:36 p.m.