KRnorm: Performs KR (Knight-Ruiz) normalization on a Hi-C matrix

Description Usage Arguments Details Value Examples

View source: R/KRnormalization.R

Description

Performs KR (Knight-Ruiz) normalization on a Hi-C matrix

Usage

1
KRnorm(A)

Arguments

A

the matrix to be normalized - any columns/rows of 0's will be removed before being normalized.

Details

Performs KR normalization. The function is a translation of the 'Matlab' code provided in the 2012 manuscript. Knight PA, Ruiz D. A fast algorithm for matrix balancing. IMA Journal of Numerical Analysis. Oxford University Press; 2012; drs019.

Value

A KR normalized matrix

Examples

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m <- matrix(rpois(100, 5), 10, 10)
KRnorm(m)

dozmorovlab/HiCdiff documentation built on May 20, 2019, 11:13 a.m.